There are approximately 11,300 newborns that die within 24 hours of their birth in the United States each year. That is 50 percent more first-day deaths than all other industrialized countries combined.
The infant mortality rate (IMR) is one of the most important indicators of the socio-economic well-being and public health conditions of a country. The US childhood immunization schedule specifies 26 vaccine doses (as of 2011-this number has drastically increased since then) for infants aged less than 1 year—the most in the world—yet 33 nations have lower IMRs.
Despite the United States spending more per capita on health care than any other country, 433 nations have better infant mortality rates. Some countries have IMRs that are less than half the US rate: Singapore, Sweden, and Japan are below 2.80. According to the Centers for Disease Control and Prevention (CDC), “The relative position of the United States in comparison to countries with the lowest infant mortality rates appears to be worsening.”
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170075/
Shedding of Vaccines – Articles
Transmission of mumps virus from mumps-vaccinated individuals to close contacts
Mumps viral titers in oral fluid are higher for unvaccinated than for vaccinated patients.
http://www.sciencedirect.com/science/article/pii/S0264410X11015428
Detection of the measles virus RNA in urine specimens from vac recipients:
Analysis of urine specimens by using reverse transcriptase-PCR was evaluated as a rapid assay to identify individuals infected with measles virus. For the study, daily urine samples were obtained from either 15 month old children or young adults following measles immunization. Overall, measles virus RNA was detected in 10 of 12 children during the 2-week sampling period. In some cases, measles virus RNA was detected as early as 1 day or as late as 14 days after injection. Measles virus RNA was also detected in the urine samples from all four of the young adults between 1 and 13 days after injection. This assay will enable continued studies of the shedding and transmission of measles virus and, it is hoped, will provide a rapid means to identify measles infection, especially in mild or asymptomatic cases.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC228449/
MMR Precautions and Warnings-I for one was never told any of this before my kids received this vaccine. Which is funny because this should be included with informed consent (that I was never given).
Febrile Seizure
There is a risk of fever and associated febrile seizure in the first 2 weeks following injection with
M-M-R II vaccine. For children who have experienced a previous febrile seizure (from any cause) and those with a family history of febrile seizures there is a small increase in risk of febrile seizure following receipt of MMR II vaccine.
Hypersensitivity to Eggs
Individuals with a history of anaphylactic, anaphylactoid, or other immediate reactions (e.g., hives,
swelling of the mouth and throat, difficulty breathing, low blood pressure, or shock) subsequent to egg ingestion may be at an increased risk of immediate-type hypersensitivity reactions after receiving M-M-R II vaccine.
The potential risks and known benefits should be evaluated before considering injection in these
individuals. Yet, why is it not?
Thrombocytopenia
Transient thrombocytopenia has been reported within 4-6 weeks following injection with measles,
mumps and rubella vaccine. Carefully evaluate the potential risk and benefit of vaccination in children with thrombocytopenia or in those who experienced thrombocytopenia after injection with a previous dose of measles, mumps, and rubella vaccine.
Family History of Immunodeficiency
Vaccination should be deferred in individuals with a family history of congenital or hereditary
immunodeficiency until the individual’s immune status has been evaluated and the individual has been found to be immunocompetent.
Immune Globulins and Transfusions
Immune Globulins (IG) and other blood products should not be given concurrently with M-M-R II. These products may contain antibodies that interfere with vaccine virus replication and decrease the expected immune response. The Advisory Committee on Immunization Practices (ACIP) has specific recommendations for intervals between administration of antibody containing products and live virus vaccines.
ADVERSE REACTIONS
The following adverse reactions include those identified during clinical trials or reported during post
approval use of M-M-R II vaccine or its individual components.
Body as a Whole
Panniculitis; atypical measles; fever; headache; dizziness; malaise; irritability.
Cardiovascular System
Vasculitis.
Digestive System
Pancreatitis; diarrhea; vomiting; parotitis; nausea.
Hematologic and Lymphatic Systems
Thrombocytopenia; purpura; regional lymphadenopathy; leukocytosis.
Immune System
Anaphylaxis, anaphylactoid reactions, angioedema (including peripheral or facial edema) and bronchial spasm.
Musculoskeletal System
Arthritis; arthralgia (joint pain); myalgia (muscle pain)
Nervous System
Encephalitis; encephalopathy; measles inclusion body encephalitis (MIBE) subacute sclerosing
panencephalitis (SSPE); Guillain-Barré Syndrome (GBS); acute disseminated encephalomyelitis (ADEM);
transverse myelitis; febrile convulsions; afebrile convulsions or seizures; ataxia; polyneuritis;
polyneuropathy; ocular palsies; paresthesia; syncope.
Respiratory System
Pneumonia; pneumonitis; sore throat; cough; rhinitis.
Skin
Stevens-Johnson syndrome; acute hemorrhagic edema of infancy; Henoch-Schönlein purpura;
erythema multiforme; urticaria; rash; measles-like rash; pruritus; injection site reactions (pain, erythema, swelling and vesiculation).
Special Senses — Ear-for anyone who says that vaccines do not cause ear infections-I disagree
Nerve deafness; otitis media
Special Senses — Eye
Retinitis; optic neuritis; papillitis; conjunctivitis.
Urogenital System
Epididymitis; orchitis
http://www.merck.com/product/usa/pi_circulars/m/mmr_ii/mmr_ii_pi.pdf
A man was infected with Smallpox-like Virus through sex
A man in San Diego was infected with the vaccinia virus — the virus in the smallpox vaccine — in June, 2012 after having sexual contact with someone who’d recently been vaccinated, according to a new report from the Centers for Disease Control and Prevention.
What’s more, the infected man also passed the virus along to another unvaccinated individual during sexual activity, a phenomenon known as tertiary transmission, the report said.
The smallpox vaccine contains the live vaccinia virus, which is similar to smallpox but doesn’t actually cause the disease. In 1972, the United States stopped vaccinating members of the public against smallpox because the disease had been eradicated. However, in 2002, the Department of Defense resumed smallpox vaccination for its military personnel and civilian employees.
http://www.livescience.com/27560-smallpox-vaccine-spread-sex.html
Vaccinia Virus Infection After Sexual Contact with Military Smallpox Vaccinee
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5925a2.htm
Detection of fecal shedding of rotavirus vaccine in infants following their first dose of pentavalent rotavirus
Studies on rotavirus vaccine shedding and its potential transmission within households including immunocompromised individuals are needed to better define the potential risks and benefits of vaccination. We examined fecal shedding of pentavalent rotavirus vaccine (RV5) for 9 days following the first dose of vaccine in infants between 6 and 12 weeks of age. Rotavirus antigen was detected by enzyme immunoassay (EIA), and vaccine-type rotavirus was identified by nucleotide sequencing based on genetic relatedness to the RV5 VP6 gene. Stool from 22 (21.4%) of 103 children contained rotavirus antigen-positive specimens on ≥1 post-vaccination days.
Rotavirus antigen was detected as early as post-vaccination day 3 and as late as day 9, with peak numbers of shedding on post-vaccination days 6 through 8. Vaccine-type rotavirus was detected in all 50 antigen-positive specimens and 8 of 8 antigen-negative specimens. Nine (75%) of 12 EIA-positive and 1 EIA-negative samples tested culture-positive for vaccine-type rotavirus. Fecal shedding of rotavirus vaccine virus after the first dose of RV5 occurred over a wide range of post-vaccination days not previously studied. These findings will help better define the potential for horizontal transmission of vaccine virus among immunocompromised household contacts of vaccinated infants for future studies.
http://www.sciencedirect.com/science/article/pii/S0264410X11004567
RotaTeq (Rotavirus Vac, Live, Oral, Pentavalent) Oral Solution:
Most common adverse events included diarrhea, vomiting, irritability, otitis media, nasopharyngitis, and bronchospasm. My daughter had 6 ear infections in the year following her kindergarten shots. And I was told that it was a coincidence, and they were not at all related to the vaccines. Yet, I am finding information that is contradicting that statement and in fact could be the very reason for her ear infections.
http://www.merck.com/product/usa/pi_circulars/r/rotateq/rotateq_pi.pdf
Breastfeeding May Transmit Vac Virus
A Canadian doctor reports breastfeeding seems to have transmitted a mother’s live-virus yellow fever vaccine virus to her baby.
Dr. Susan Kuhn of the University of Calgary says this incident affirms current recommendations breastfeeding mothers avoid the yellow fever vaccine — in use since the 1940s — because it is a live-virus vaccine.
Chicken Pox (Varivax) – Shedding (Section 5.4)
Risk of Vaccine Virus Transmission Post-marketing experience suggests that transmission of varicella vaccine virus (Oka/Merck) resulting in varicella infection including disseminated disease may occur between vaccine recipients (who develop or do not develop a varicella-like rash) and contacts susceptible to varicella including healthy as well as high-risk individuals. Due to the concern for transmission of vaccine virus, vaccine recipients should attempt to avoid whenever possible close association with susceptible high-risk individuals for up to six weeks following vaccination with VARIVAX. Susceptible high-risk individuals include: • Immunocompromised individuals; • Pregnant women without documented history of varicella or laboratory evidence of prior infection; • Newborn infants of mothers without documented history of varicella or laboratory evidence of prior infection and all newborn infants born at <28 weeks gestation regardless of maternal varicella immunity.
http://www.merck.com/product/usa/pi_circulars/v/varivax/varivax_pi.pdf
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